Emergence of a Cell Line With Extreme
نویسنده
چکیده
Cytogenetic studies in a patient with banding confirmed complex chromosome chronic myelocytic leukemia (CML) demonrearrangements and demonstrated distinct strated the emergence of an extremely banding patterns for the marker chromehypodiploid cell line at the time of blast somes. Cytologic characteristics of the crisis, a modal chromosome number of 35, leukemia blasts were predominantly myewith the modal karyotype 35.XY. -3, bid. There was no important clinical -4.5. 7, 9. 1 1 . 12.1 3,1 5. response to chemotherapy. including yin16,17,19,-20,-22,+t(9;22) cristine and prednisone. or to radiothera(q34;ql 1 ). + Mar1 . + Mar2. + Mar3. Giemsapy.
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متن کاملEmergence of a cell line with extreme hypodiploidy in blast crisis of chronic myelocytic leukemia.
Cytogenetic studies in a patient with chronic myelocytic leukemia (CML) demonstrated the emergence of an extremely hypodiploid cell line at the time of blast crisis, a modal chromosome number of 35, with the modal karyotype 35,XY, -3, -4, -5, -7, -9, -11, -12, -13, -15, -16, -17, -19, -20, -22, + t(9;22) (q34;q11, + Mar1, + Mar2, + Mar3. Giemsa-banding confirmed complex chromosome rearrangement...
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تاریخ انتشار 2005